Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes

1 Nov 1995

Abstract excerpt

The C fragment C5a exerts its important physiologic and pathologic effects through interaction with a specific C5a receptor (C5aR) which is highly expressed on polymorphonuclear leukocytes and some other leukocytes. The presence of this receptor on epithelia and endothelia has recently been documented, raising the possibility that these other cells might also respond to locally generated C5a. C has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Coagulation and Thrombosis Mechanisms
Share to Complement system in diseases
Share to Inflammation biomarkers and pathways

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7594492
DOI: 10.4049/jimmunol.155.10.4882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytesPMID 7594492Read ↗

Identification and characterization of complement C3 receptors on human astrocytesSemantic proximity Read ↗

The Receptor for Complement Anaphylatoxin C3a Is Expressed by Myeloid Cells and Nonmyeloid Cells in Inflamed Human Central Nervous System: Analysis in Multiple Sclerosis and Bacterial MeningitisSemantic proximity Read ↗

The Complement System: A Powerful Modulator and Effector of Astrocyte Function in the Healthy and Diseased Central Nervous System.Semantic proximity Read ↗

Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines.Semantic proximity Read ↗

An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2.Semantic proximity Read ↗

The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factorsSemantic proximity Read ↗

Functional PAF receptors in glia cells: binding parameters and regulation of expression.Semantic proximity Read ↗

Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway.Semantic proximity Read ↗

Complement Peptide C3a Promotes Astrocyte Survival in Response to Ischemic Stress.Semantic proximity Read ↗

Disruption of the C5a receptor gene fails to protect against experimental allergic encephalomyelitis.Semantic proximity Read ↗

A post-inflammatory C3-high astrocyte state persists after inflammatory stimulus withdrawal and is attenuated by JAK inhibitionSemantic proximity Read ↗

Measles virus receptor properties are shared by several CD46 isoforms differing in extracellular regions and cytoplasmic tails.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.