Article
Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism - 1 Apr 2002
Ehrmann David A, Schwarz Peter E H, Hara Manami, Tang Xu, Horikawa Yukio, Imperial Jacqueline, Bell Graeme I, Cox Nancy J
Abstract excerpt
Polycystic ovary syndrome (PCOS) is associated with an increased risk of impaired glucose tolerance and type 2 diabetes. Recent evidence suggests that variation in the gene encoding the cysteine protease calpain-10 influences susceptibility to type 2 diabetes. The present study was undertaken to determine whether variation in this gene is associated with quantitative traits pertinent to the pathogenesis of PCOS...
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