Article
Association of CAPN10 SNPs and haplotypes with polycystic ovary syndrome among South Indian Women.
PloS one - 1 Jan 2012
Dasgupta Shilpi, Sirisha Pisapati V S, Neelaveni Kudugunti, Anuradha Katragadda, Reddy B Mohan
Abstract excerpt
Polycystic Ovary Syndrome (PCOS) is known to be characterized by metabolic disorder in which hyperinsulinemia and peripheral insulin resistance are central features. Given the physiological overlap between PCOS and type-2 diabetes (T2DM), and calpain 10 gene (CAPN10) being a strong candidate for T2DM, a number of studies have analyzed CAPN10 SNPs among PCOS women yielding contradictory results. Our study is first...
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