Article
Haplotype combinations of calpain 10 gene polymorphisms associate with increased risk of impaired glucose tolerance and type 2 diabetes in South Indians.
Diabetes - 1 May 2002
Cassell Paul G, Jackson Alan E, North Bernard V, Evans Julie C, Syndercombe-Court Denise, Phillips Chris, Ramachandran Ambady, Snehalatha Chamukuttan, Gelding Susan V, Vijayaravaghan Shanti, Curtis David, Hitman Graham A
Abstract excerpt
Haplotype combination 112/121 and its intrinsic variants (UCSNP43, -19, and -63) identified within the calpain 10 gene are associated with increased risk of type 2 diabetes in Mexican-Americans. We evaluated whether this haplotype combination and its constituent haplotypes and variants contribute to increased susceptibility to impaired fasting glucose (IFG)/impaired glucose tolerance (IGT) and type 2 diabetes in...
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