Article
Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians.
American journal of physiology. Endocrinology and metabolism - 1 Mar 2007
Vollmert Caren, Hahn Susanne, Lamina Claudia, Huth Cornelia, Kolz Melanie, Schöpfer-Wendels Andreas, Mann Klaus, Bongardt Friedhelm, Mueller Jakob C, Kronenberg Florian, Wichmann H-Erich, Herder Christian, Holle Rolf, Löwel Hannelore, Illig Thomas, Janssen Onno E
Abstract excerpt
PCOS is known to be associated with an increased risk of T2DM and has been proposed to share a common genetic background with T2DM. Recent studies suggest that the Calpain-10 gene (CAPN10) is an interesting candidate gene for PCOS susceptibility. However, contradictory results were reported concerning the contribution of certain CAPN10 variants, especially of UCSNP-44, to genetic predisposition to T2DM,...
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