Article
Association analysis of calpain 10 gene variants/haplotypes with gestational diabetes mellitus among Mexican women.
Cellular and molecular biology (Noisy-le-Grand, France) - 28 Feb 2018
Castro-Martínez Anna Gabriela, Sánchez-Corona José, Vázquez-Vargas Adriana Patricia, García-Zapién Alejandra Guadalupe, López-Quintero Andres, Villalpando-Velazco Héctor Javier, Flores-Martínez Silvia Esperanza
Abstract excerpt
Gestational diabetes mellitus (GDM) is a metabolically complex disease with major genetic determinants. GDM has been associated with insulin resistance and dysfunction of pancreatic beta cells, so the GDM candidate genes are those that encode proteins modulating the function and secretion of insulin, such as that for calpain 10 (CAPN10). This study aimed to assess whether single nucleotide polymorphism (SNP)-43,...
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