Article
Drosophila liprin-alpha and the receptor phosphatase Dlar control synapse morphogenesis.
Neuron - 28 Mar 2002
Kaufmann Nancy, DeProto Jamin, Ranjan Ravi, Wan Hong, Van Vactor David
Abstract excerpt
Here, we examine the synaptic function of the receptor protein tyrosine phosphatase (RPTP), Dlar, and an associated intracellular protein, Dliprin-alpha, at the Drosophila larval neuromuscular junction. We show that Dliprin-alpha and Dlar are required for normal synaptic morphology. We also find that synapse complexity is proportional to the amount of Dlar gene product, suggesting that Dlar activity determines...
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