Article
The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila.
Cell - 23 Feb 1996
Krueger N X, Van Vactor D, Wan H I, Gelbart W M, Goodman C S, Saito H
Abstract excerpt
DLAR is a receptor-like, transmembrane protein-tyrosine phosphatase in Drosophila that is expressed almost exclusively by developing neurons. Analysis of Dlar loss-of-function mutations shows that DLAR plays a key role during motoneuron growth cone guidance. Segmental nerve b (SNb) motor axons normally exit the common motor pathway, enter the ventral target region, and then synapse on specific ventral muscles. In...
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