Article
The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila.
Cell - 23 Feb 1996
Krueger N X, Van Vactor D, Wan H I, Gelbart W M, Goodman C S, Saito H
Abstract excerpt
DLAR is a receptor-like, transmembrane protein-tyrosine phosphatase in Drosophila that is expressed almost exclusively by developing neurons. Analysis of Dlar loss-of-function mutations shows that DLAR plays a key role during motoneuron growth cone guidance. Segmental nerve b (SNb) motor axons no...
Topics
- Amino Acid Sequence
- Animals
- Axons
- Base Sequence
- Central Nervous System
- Chromosome Mapping
- Drosophila
- Genes, Insect
- Molecular Sequence Data
- Motor Neurons
- Mutagenesis
- Neural Pathways
- Phenotype
- Protein Tyrosine Phosphatases
- Receptor-Like Protein Tyrosine Phosphatases, Class 4
- Receptors, Cell Surface