Article
Allele frequencies of apolipoprotein E gene polymorphisms in the protein coding region and promoter region (-491A/T) in a healthy Norwegian population.
Human biology - 1 Feb 2002
Kumar Theresa, Liestøl Knut, Maehlen Jan, Hiorth Aksel, Jettestuen Espen, Lind Helge, Brorson Sverre-Henning
Abstract excerpt
This study examines the distribution of apolipoprotein E (APOE) alleles in a population of healthy male and female Norwegians (n = 798) below the age of 40. The -491A/T polymorphism of the promoter region of the APOE gene was also examined. A seminested polymerase chain reaction was applied in the genotyping. The results showed that the E3 allele had the highest frequency (0.744), followed by E4 (0.198) and E2...
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