Article
Association of polymorphism in the promoter region of the apolipoprotein E gene with diastolic blood pressure in normotensive Japanese.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 May 2000
Katsuya T, Sato N, Asai T, Fukuda M, Takiuchi S, Fu Y, Hanayama R, Moriguchi A, Rakugi H, Higaki J, Ogihara T
Abstract excerpt
The epsilon4 allele of apolipoprotein E (APOE) is reported to be a genetic risk factor of atherosclerosis through hyperlipidemia and late-onset Alzheimer's dementia. A recent report showed that a genetic variant (A -491T) in the promoter region of the APOE gene increases the risk of Alzheimer's disease. In the present study, we examined whether these APOE polymorphisms were genetically involved in essential...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.