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Article

Multilevel Control of Competence Development and Stress Tolerance in <i>Streptococcus mutans</i> UA159

23 Feb 2006

Abstract excerpt

Genetic competence appears to be important in establishment of biofilms and tolerance of environmental insults. We report here that the development of competence is controlled at multiple levels in a complex network that includes two signal-transducing two-component systems (TCS). Using Streptococcus mutans strain UA159, we demonstrate that the histidine kinase CiaH, but not the response regulator CiaR, causes a...

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PMID: 16495534
DOI: 10.1128/iai.74.3.1631-1642.2006

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