Article
Cigarette smoking and other risk factors in relation to p53 expression in breast cancer among young women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 1999
Gammon M D, Hibshoosh H, Terry M B, Bose S, Schoenberg J B, Brinton L A, Bernstein J L, Thompson W D
Abstract excerpt
p53 mutations may be a fingerprint for cigarette smoking and other environmental carcinogens, including breast carcinogens. This study was undertaken to explore whether p53 mutations are associated with environmental or other suspected or established risk factors for breast cancer. p53 protein detection by immunohistochemistry (which is more easily quantified in large epidemiological studies than are mutations,...
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