Article
Biallelic inactivation of the thyroid hormone receptor beta1 gene in early stage breast cancer.
Cancer research - 1 Apr 2002
Li Zheng, Meng Zhen Hang, Chandrasekaran Raman, Kuo Wen-Lin, Collins Colin C, Gray Joe W, Dairkee Shanaz H
Abstract excerpt
Loss of heterozygosity within the short arm of chromosome 3 is a common molecular event in several types of solid tumors. In breast cancer, 3p loss of heterozygosity occurs in invasive tumor cells as well as in morphologically normal terminal ductal lobular units adjacent to carcinoma in some cases [G. Deng et al., Science (Wash. DC), 274: 2057-2059, 1996.]. The most frequent region of allelic loss at 3p24.3 in...
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