Studies of allelic loss in thyroid tumors reveal major differences in chromosomal instability between papillary and follicular carcinomas.

doi:10.1210/jcem.83.2.4550

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Article

Studies of allelic loss in thyroid tumors reveal major differences in chromosomal instability between papillary and follicular carcinomas.

The Journal of clinical endocrinology and metabolism - 1 Feb 1998

Ward L S, Brenta G, Medvedovic M, Fagin J A

Abstract excerpt

Loss of heterozygosity (LOH) studies have been used to identify sites harboring tumor suppressor genes involved in tumor initiation or progression. Previous reports have suggested that regions within chromosomes 3p, 11q, 2p, 2q, 10q, and 1p may be frequently deleted in human follicular thyroid ce...

Topics

Adenocarcinoma, Follicular
Alleles
Carcinoma, Papillary
Chromosomes, Human, Pair 10
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 16
Chromosomes, Human, Pair 2
Chromosomes, Human, Pair 3
Gene Deletion
Humans
Loss of Heterozygosity
Thyroid Neoplasms

Source

Open in PubMed

Identifiers

PMID: 9467569
DOI: 10.1210/jcem.83.2.4550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9467569-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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