Article
Direct interaction between uracil-DNA glycosylase and a proliferating cell nuclear antigen homolog in the crenarchaeon Pyrobaculum aerophilum.
The Journal of biological chemistry - 21 Jun 2002
Yang Hanjing, Chiang Ju-Huei, Fitz-Gibbon Sorel, Lebel Michel, Sartori Alessandro A, Jiricny Joseph, Slupska Malgorzata M, Miller Jeffrey H
Abstract excerpt
Proliferating cell nuclear antigen (PCNA) acts as a sliding clamp on duplex DNA. Its homologs, present in Eukarya and Archaea, are part of protein complexes that are indispensable for DNA replication and DNA repair. In Eukarya, PCNA is known to interact with more than a dozen different proteins, including a human major nuclear uracil-DNA glycosylase (hUNG2) involved in immediate postreplicative repair. In...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
