Article
The BRCA2 372 HH genotype is associated with risk of breast cancer in Australian women under age 60 years.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2002
Spurdle Amanda B, Hopper John L, Chen Xiaoqing, Dite Gillian S, Cui Jisheng, McCredie Margaret R E, Giles Graham G, Ellis-Steinborner Sarah, Venter Deon J, Newman Beth, Southey Melissa C, Chenevix-Trench Georgia
Abstract excerpt
The BRCA2 N372H nonconservative amino acid substitution polymorphism appears to affect fetal survival in a sex-dependent manner, and the HH genotype was found to be associated with a 1.3-fold risk of breast cancer from pooling five case-control studies of Northern European women. We investigated whether the BRCA2 N372H polymorphism was associated with breast cancer in Australian women using a population-based...
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