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Article

Association of BRCA2 N372H polymorphism with cancer susceptibility: a comprehensive review and meta-analysis.

Scientific reports - 28 Oct 2014

Xue Wen-Qiong, He Yong-Qiao, Zhu Jin-Hong, Ma Jian-Qun, He Jing, Jia Wei-Hua

Abstract excerpt

BRCA2 gene plays an important role in homologous recombination. Polymorphic variants in this gene has been suggested to confer cancer susceptibility. Numerous studies have investigated association between BRCA2 N372H polymorphism and risk of several cancers, especially breast cancer. However, the results were inconsistent. We performed a comprehensive meta-analysis to provide a more precise assessment of the...

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Share to BRCA2 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25348552
DOI: 10.1038/srep06791
PMCID: PMC4210867

Genes

BRCA2

Variants

Provenance

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