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Article

BRCA2 Arg372Hispolymorphism and epithelial ovarian cancer risk.

International journal of cancer - 20 Jan 2003

Auranen Annika, Spurdle Amanda B, Chen Xiaoqing, Lipscombe Julian, Purdie David M, Hopper John L, Green Adele, Healey Catherine S, Redman Karen, Dunning Alison M, Pharoah Paul D, Easton Douglas F, Ponder Bruce A J, Chenevix-Trench Georgia, Novik Karen L

Abstract excerpt

The BRCA2 372 HH genotype defined by the BRCA2 N372H nonconservative amino acid substitution polymorphism was recently reported to be associated with a small increased risk of breast cancer. We investigated whether this polymorphism was associated with ovarian cancer risk by conducting British and Australian case-control comparisons in parallel, including a total sample of 1,121 ovarian cancer cases and 2,643...

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Share to Adenocarcinoma, Clear Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 Protein

Share to Carcinoma, Endometrioid

Share to Cystadenocarcinoma, Serous

Share to Neoplasm Invasiveness

Share to Neoplasms, Glandular and Epithelial

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Source

Identifiers

PMID: 12471628
DOI: 10.1002/ijc.10814

Genes

BRCA2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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BRCA2 Arg372Hispolymorphism and epithelial ovarian cancer risk.PMID 12471628Read ↗

BRCA2 N372H Polymorphism and Risk of Epithelial Ovarian Cancer: An Updated Meta-Analysis With 2344 Cases and 9672 Controls.Semantic proximity Read ↗

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Polymorphisms in BRCA1 and BRCA2 and risk of epithelial ovarian cancer.Semantic proximity Read ↗

The BRCA2 372 HH genotype is associated with risk of breast cancer in Australian women under age 60 years.Semantic proximity Read ↗

Common BRCA2 variants and modification of breast and ovarian cancer risk in BRCA1 mutation carriers.Semantic proximity Read ↗

Association of BRCA2 N372H polymorphism with cancer susceptibility: a comprehensive review and meta-analysis.Semantic proximity Read ↗

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