Article
Association of BRCA2 polymorphism at codon 784 (Met/Val) with breast cancer risk and prognosis.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2003
Ishitobi Makoto, Miyoshi Yasuo, Ando Akiko, Hasegawa Seiichi, Egawa Chiyomi, Tamaki Yasuhiro, Monden Morito, Noguchi Shinzaburo
Abstract excerpt
PURPOSE: The association of BRCA2 polymorphisms at codon 372 [Asn (N)/His (H)]and codon 784 [Met (M)/Val (V)] with breast cancer risk was evaluated in Japanese women. In addition, the prognostic significance of these polymorphisms was studied in breast cancer patients. EXPERIMENTAL DESIGN: A case-control study was conducted to examine the association of the BRCA2 N/H372 polymorphism and M/V 784 polymorphism with...
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