Article
The HER2 I655V polymorphism and risk of breast cancer in women < age 40 years.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2003
Montgomery Karen G, Gertig Dorota M, Baxter Simon W, Milne Roger L, Dite Gillian S, McCredie Margaret R E, Giles Graham G, Southey Melissa C, Hopper John L, Campbell Ian G
Abstract excerpt
The HER2 gene controls cellular function and has prognostic significance in breast cancer. The I655V polymorphism was associated with increased risk of breast cancer in Chinese women under the age of 45 years and in women with a first-degree family history of the disease. These associations, however, have not been confirmed in several studies of older women. We conducted a population-based case-control-family...
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