Article
Phosphoinositide 3-kinases in immunity: lessons from knockout mice.
Journal of biochemistry - 1 Apr 2002
Sasaki Takehiko, Suzuki Akira, Sasaki Junko, Penninger Josef M
Abstract excerpt
Phosphoinositide 3-kinases (PI3Ks) constitute a family of evolutionarily conserved lipid kinases that phosphorylate the D3 position of the inositol ring of phosphoinositides and produce PI(3)P, PI(3,4)P(2), and PI(3,4,5)P(3). Intense in vitro research over the last decade has unequivocally demons...
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