Article
Involvement of the alpha3 subunit in central nicotinic binding populations.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Apr 2002
Whiteaker Paul, Peterson Cyrus G, Xu Wei, McIntosh J Michael, Paylor Richard, Beaudet Arthur L, Collins Allan C, Marks Michael J
Abstract excerpt
The alpha3 subunit gene was one of the first neuronal nicotinic acetylcholine receptor (nAChR) subunits to be cloned (Boulter et al., 1986), but direct evidence of alpha3 subunit contributions to mammalian central nAChR populations has not been presented. The studies reported here used mice engineered to contain a null mutation in the alpha3 nAChR subunit gene (Xu et al., 1999) to examine the involvement of the...
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