Article
Organization of the mouse 5-HT3 receptor gene and functional expression of two splice variants.
Brain research. Molecular brain research - 1 Oct 1994
Werner P, Kawashima E, Reid J, Hussy N, Lundström K, Buell G, Humbert Y, Jones K A
Abstract excerpt
The structure of the mouse 5-HT3 receptor gene, 5-HT3R-A, is most similar to nicotinic acetylcholine receptor (nAChR) genes, in particular to the gene encoding the neuronal nAChR subunit alpha 7. These genes share among other things the location of three adjacent introns, suggesting that 5-HT3R-A and nAChR genes arose from a common precursor gene. The alternative use of two adjacent splice acceptor sites in...
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