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Article

Roles of accessory subunits in alpha4beta2(*) nicotinic receptors.

Molecular pharmacology - 1 Jul 2008

Kuryatov Alexandre, Onksen Jennifer, Lindstrom Jon

Abstract excerpt

Accessory subunits in heteromeric nicotinic receptors (AChRs) do not take part in forming ACh binding sites. alpha5 and beta3 subunits can function only as accessory subunits. We show that both alpha5 and beta3 efficiently assemble in human alpha4beta2(*) AChRs expressed in permanently transfected human embryonic kidney (HEK) cell lines. Only (alpha4beta2)(2)alpha5, not (alpha4beta2)(2)beta3 AChRs, have been...

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Identifiers

PMID: 18381563
DOI: 10.1124/mol.108.046789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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