Article
Evidence for the presence of mutagenic arylamines in human breast milk and DNA adducts in exfoliated breast ductal epithelial cells.
Environmental and molecular mutagenesis - 1 Jan 2002
Thompson Patricia A, DeMarini David M, Kadlubar Fred F, McClure Gail Y, Brooks Lance R, Green Bridgett L, Fares Manal Y, Stone Angie, Josephy P David, Ambrosone Christine B
Abstract excerpt
Aromatic and heterocyclic amines are ubiquitous environmental mutagens present in combustion emissions, fried meats, and tobacco smoke, and are suspect human mammary carcinogens. To determine the presence of arylamines in breast tissue and fluid, we examined exfoliated breast ductal epithelial cells for DNA adducts and matched human milk samples for mutagenicity. Breast milk was obtained from 50 women who were...
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