Article
Behavioral analysis of CREB alphadelta mutation on a B6/129 F1 hybrid background.
Hippocampus - 1 Jan 2002
Graves L, Dalvi A, Lucki I, Blendy J A, Abel T
Abstract excerpt
The cyclic AMP (cAMP)-response element binding protein (CREB) is an activity-dependent transcription factor that plays a role in synaptic plasticity and memory storage in Aplysia, Drosophila, and rodents. Mice with targeted deletions of two CREB isoforms (alpha and delta; CREB alphadelta mice) have been characterized on a mixed genetic background of C57BL/6 (B6) and 129/SvEv (129), as well as on a defined F1...
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