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Article

Genetic architecture of fear conditioning in chromosome substitution strains: relationship to measures of innate (unlearned) anxiety-like behavior.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2007

Ponder Christine A, Munoz Michaelanne, Gilliam T Conrad, Palmer Abraham A

Abstract excerpt

We measured fear conditioning (FC) in a panel of chromosome substitution strains (CSS) created using the C57BL/6J (B6) and A/J (AJ) inbred strains. Mice were trained to associate a specific context and tone with a foot shock. FC was measured by observing freezing behavior during re-exposure to the context and tone. Freezing to context was more than twofold greater in the AJ strain relative to the B6 strain. Among...

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Share to Anxiety
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mice, Inbred Strains

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Source

Identifiers

PMID: 17492333
DOI: 10.1007/s00335-007-9013-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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