Article
Catalog of 434 single-nucleotide polymorphisms (SNPs) in genes of the alcohol dehydrogenase, glutathione S-transferase, and nicotinamide adenine dinucleotide, reduced (NADH) ubiquinone oxidoreductase families.
Journal of human genetics - 1 Jan 2001
Iida A, Saito S, Sekine A, Kitamoto T, Kitamura Y, Mishima C, Osawa S, Kondo K, Harigae S, Nakamura Y
Abstract excerpt
An approach based on development of a large archive of single-nucleotide polymorphisms (SNPs) throughout the human genome is expected to facilitate large-scale studies to identify genes associated with drug efficacy and side effects, or susceptibility to common diseases. We have already described collections of SNPs present among various genes encoding drug-metabolizing enzymes. Here we report SNPs for such...
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