Article
Single nucleotide polymorphisms in alcohol dehydrogenase genes among some Indian populations.
American journal of human biology : the official journal of the Human Biology Council - 1 Jan 2000
Rao V R, Bhaskar L V K S, Annapurna C, Reddy A G, Thangaraj K, Rao A Papa, Singh Lalji
Abstract excerpt
Seven ADH genes, identified until now, located in the long arm of human chromosome 4, produce seven different isozymes involved in the metabolism of ethanol to acetaldehyde. Of the more than 500 SNPs reported in the coding and non-coding regions of these genes in the world databases, 11 are more extensively studied. Three SNPs, ADH1B Arg47His (Exon3), ADH1B Arg369Cys (Exon9) and ADH1C Val349Ile (Exon8), are...
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