Article
Microsatellite Instability in Yeast: Dependence on the Length of the Microsatellite
1 Jul 1997
Abstract excerpt
One of the most common microsatellites in eukaryotes consists of tandem arrays [usually 15-50 base pairs (bp) in length] of the dinucleotide GT. We examined the rates of instability for poly GT tracts of 15, 33, 51, 99 and 105 bp in wild-type and mismatch repair-deficient strains of Saccharomyces cerevisiae. Rates of instability increased more than two orders of magnitude as tracts increased in size from 15 to 99...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
