Article
Association of allelic loss at 8p22 with poor prognosis among breast cancer cases treated with high-dose adjuvant chemotherapy.
Cancer letters - 6 Jun 2002
Tsuneizumi Michiko, Emi Mitsuru, Hirano Akira, Utada Yoshihito, Tsumagari Koji, Takahashi Kaoru, Kasumi Fujio, Akiyama Futoshi, Sakamoto Goi, Kazui Teruhisa, Nakamura Yusuke
Abstract excerpt
To identify specific allelic losses that might correlate with postoperative mortality of breast cancer patients treated with high-dose adjuvant chemotherapy consisting of cyclophosphamide, methotrexate and fluorouracil, we examined tumors from a cohort of 150 such patients, who were followed clinically for 5 years postoperatively, for allelic losses (loss of heterozygosity, LOH) among 18 microsatellite markers...
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