Article
Allelic loss at the 8p22 region as a prognostic factor in large and estrogen receptor negative breast carcinomas.
Cancer - 15 Mar 2000
Utada Y, Haga S, Kajiwara T, Kasumi F, Sakamoto G, Nakamura Y, Emi M
Abstract excerpt
BACKGROUND: Allelic losses of tumor suppressor genes, or the chromosomal regions harboring them, in the DNA of tumor cells may become useful postoperative prognostic indicators. The authors studied frequent loss of heterozygosity (LOH) on chromosome 8p22 and its association with disease progression that occurred later in patients with breast carcinoma. METHODS: To examine whether allelic losses at 8p22 might...
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