Article
Association of a functional inducible nitric oxide synthase promoter variant with complications in type 2 diabetes.
Journal of molecular medicine (Berlin, Germany) - 1 Feb 2002
Morris Brian J, Markus AndreaM, Glenn Cheryl L, Adams David J, Colagiuri S, Wang Li
Abstract excerpt
Complications of diabetes have a genetic influence. Since increased inducible nitric oxide synthase (iNOS) gene ( NOS2A) expression can contribute to tissue damage, NOS2A is a worthy candidate for such a role. We therefore tested a 4-bp insertion/deletion (+/-) polymorphism 0.7 kb upstream of NOS...
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