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Article

eNOS gene polymorphism association with retinopathy in type 1 diabetes.

Ophthalmic genetics - 1 Sept 2010

Bazzaz Javad Tavakkoly, Amoli Mahsa M, Pravica Vera, Chandrasecaran Ramesh, Boulton Andrew J, Larijani Bagher, Hutchinson Ian V

Abstract excerpt

PURPOSE: Nitric oxide (NO) is a major mediator in vascular biology, regulating blood pressure and regional blood flow. NO and the enzymes required for its production may contribute to the aetiology of vascular pathologies. In diabetes, over-production of NO might play a role in the development of diabetic nephropathy, while reduced NO production may be related to the development of diabetic retinopathy and...

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Cross-Sectional Studies
Diabetes Mellitus, Type 1
Diabetic Retinopathy
Nitric Oxide Synthase Type III
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

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PMID: 20565248
DOI: 10.3109/13816810.2010.482553

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