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Article

Genotyping and functional analysis of a polymorphic (CCTTT) <sub>n</sub> repeat of NOS2A in diabetic retinopathy

1 Oct 1999

Abstract excerpt

Accumulating evidence shows that the severity and rapidity of onset of diabetic retinopathy are influenced by genetic factors. Expression of the nitric oxide synthases is altered in the retinal vasculature in the early stages of diabetic retinopathy. We analyzed the allele distribution of a polymorphic pentanucleotide repeat within the 5' upstream promoter region of the NOS2A gene in samples of diabetic patients....

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PMID: 10506586
DOI: 10.1096/fasebj.13.13.1825

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