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Article

Negative prognostic value of glutathione S-transferase (GSTM1 and GSTT1) deletions in adult acute myeloid leukemia.

Blood - 15 Oct 2002

Voso Maria Teresa, D'Alo' Francesco, Putzulu Rossana, Mele Luca, Scardocci Alessandra, Chiusolo Patrizia, Latagliata Roberto, Lo-Coco Francesco, Rutella Sergio, Pagano Livio, Hohaus Stefan, Leone Giuseppe

Abstract excerpt

Glutathione S-transferases (GSTs) are enzymes involved in the detoxification of several environmental mutagens, carcinogens, and anticancer drugs. GST polymorphisms resulting in decreased enzymatic activity have been associated with several types of solid tumors. We determined the prognostic significance of the deletion of 2 GST subfamilies genes, M1 and T1, in patients with acute myeloid leukemia (AML). Using...

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Source

Identifiers

PMID: 12351375
DOI: 10.1182/blood.V100.8.2703

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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