Article
Risk effects of GST gene polymorphisms in patients with acute myeloid leukemia: a prospective study.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Zhou Lei, Zhu Yan-Yun, Zhang Xiao-Dong, Li Yang, Liu Zhuo-Gang
Abstract excerpt
Glutathione S-transferase (GST) enzyme levels are associated with risk of many cancers, including hematologic tumours. We here aimed to investigate the relationships between GSTM1, GSTT1 and GSTP1 polymorphisms and the risk of AML. Genotyping of GSTs was based upon duplex polymerase-chain-reactions with the confronting- two-pair primer (PCR-CTPP) method in 163 cases and 204 controls. Individuals carrying null...
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