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Article

[The effects of glutathione S-transferase (GSTT1 and GSTM1) genes polymorphisms on treatment efficacy and prognosis of acute myeloid leukemia].

Zhonghua nei ke za zhi - 1 Mar 2006

Zhang Yue, Yang Lin, Li Rui, Zhang Li, Zhang Mei-rong, Xiao Zhi-jian

Abstract excerpt

OBJECTIVE: To investigate the impact of GSTT1 and GSTM1 genotypes on response, drug side effects and prognosis of acute myeloid leukemia (AML). METHODS: GSTT1 and GSTM1 genotypes were analysed in 180 AML patients with PCR. Complete remission (CR) rate, drug side-effects, overall survival, relapse-free survival and relapse rate were compared in groups with or without GSTT1 and GSTM1 genes. RESULTS: (1) The CR rate...

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Source

Identifiers

PMID: 16624155

Genes

GSTT1
GSTM1

Provenance

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