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Article

Mutation of the myosin converter domain alters cross-bridge elasticity.

Proceedings of the National Academy of Sciences of the United States of America - 19 Mar 2002

Köhler Jan, Winkler Gerhard, Schulte Imke, Scholz Tim, McKenna William, Brenner Bernhard, Kraft Theresia

Abstract excerpt

Elastic distortion of a structural element of the actomyosin complex is fundamental to the ability of myosin to generate motile forces. An elastic element allows strain to develop within the actomyosin complex (cross-bridge) before movement. Relief of this strain then drives filament sliding, or...

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Share to Cardiomyopathy, Hypertrophic, Familial
Share to Elasticity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle Fibers, Skeletal

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Identifiers

PMID: 11904418
DOI: 10.1073/pnas.062415899
PMCID: PMC122562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11904418-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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