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Article

Association of a common polymorphism in the human GH1 gene with colorectal neoplasia.

Journal of the National Cancer Institute - 20 Mar 2002

Le Marchand Loïc, Donlon Timothy, Seifried Ann, Kaaks Rudolf, Rinaldi Sabina, Wilkens Lynne R

Abstract excerpt

BACKGROUND: Growth hormone (GH) may be associated with the development of colorectal tumors directly and/or indirectly via an increased plasma level of insulin-like growth factor-I (IGF-I), which has been associated with colorectal cancer risk. Because a T-to-A polymorphism in the human GH1 gene at position 1663 is putatively associated with lower levels of GH and IGF-I, we investigated the relationship of this...

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Source

Identifiers

PMID: 11904318
DOI: 10.1093/jnci/94.6.454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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