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Article

Insulin-like growth factor-1 promoter polymorphisms and colorectal cancer: a functional genomics approach.

Gut - 1 Aug 2008

Wong H-L, Koh W-P, Probst-Hensch N M, Van den Berg D, Yu M C, Ingles S A

Abstract excerpt

RATIONALE: Insulin-like growth factor-1 (IGF1) has been proposed to mediate the obesity-related carcinogenic effects of "Western lifestyle". While genetic factors explain at least half of inter-individual IGF1 variation, the IGF1 polymorphisms hypothesised to underlie the variation in cancer incidence rates remain ill-defined. METHODS: We used a comparative genomics approach to identify putative regulatory...

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Source

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Identifiers

PMID: 18308828
DOI: 10.1136/gut.2007.140855
PMCID: PMC2752962

Genes

IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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