Article
Effect of apolipoprotein E genotype on hippocampal volume loss in aging healthy women.
Neurology - 26 Dec 2001
Cohen R M, Small C, Lalonde F, Friz J, Sunderland T
Abstract excerpt
OBJECTIVE: To determine whether the presence of a single epsilon4 allele of the APOE gene is associated with an increased rate of hippocampal volume loss or decline in cognition in healthy women in their sixth decade of life. METHODS: Nine APOE-epsilon4 allele-negative (mean age +/- SD, 60.6 +/- 10.2 years) and 16 APOE-epsilon4 allele-positive (mean age +/- SD, 55.1 +/- 6.0 years) healthy women underwent...
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