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Article

A novel role for Gq alpha in alpha-thrombin-mediated mitogenic signalling pathways.

Cellular signalling - 1 Jun 2002

Gardner Alice, Phillips-Mason Polly J, Raben Daniel M, Baldassare Joseph J

Abstract excerpt

alpha-Thrombin activates several G-proteins including members of the Gq, Gi, and G12/13 families, although the physiological importance of these proteins is still not completely understood. We specifically investigated the role of Gq alpha in modulating alpha-thrombin-induced mitogenesis. In Gqa1 cells, a stable cell line expressing reduced amounts of Gq alpha, concentrations of alpha-thrombin (1 NIH unit/ml),...

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PMID: 11897490
DOI: 10.1016/s0898-6568(01)00279-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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