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Article

Nuclear diacylglycerol kinase-theta is activated in response to alpha-thrombin.

The Journal of biological chemistry - 29 Jun 2001

Bregoli L, Baldassare J J, Raben D M

Abstract excerpt

Currently, there is substantial evidence that nuclear lipid metabolism plays a critical role in a number of signal transduction cascades. Previous work from our laboratory showed that stimulation of quiescent fibroblasts with alpha-thrombin leads to the production of two lipid second messengers in the nucleus: an increase in nuclear diacylglycerol mass and an activation of phospholipase D, which catalyzes the...

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PMID: 11309392
DOI: 10.1074/jbc.M101501200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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