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Article

Biological and genetic evolution of HIV type 1 in two siblings with different patterns of disease progression.

AIDS research and human retroviruses - 1 Dec 2007

Ripamonti Chiara, Leitner Thomas, Laurén Anna, Karlsson Ingrid, Pastore Angela, Cavarelli Mariangela, Antonsson Liselotte, Plebani Anna, Fenyö Eva Maria, Scarlatti Gabriella

Abstract excerpt

To investigate the immunological and virological factors that may lead to different patterns of disease progression characteristic of HIV-1-infected children, two HIV-1-infected siblings, a slow and a fast progressor, were followed prospectively before the onset of highly active antiretroviral therapy. Viral coreceptor usage, including the use of CCR5/CXCR4 chimeric receptors, macrophage tropism, and sensitivity...

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Source

Identifiers

PMID: 18160011
DOI: 10.1089/aid.2006.0215

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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