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Article

Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer.

Oncogene - 14 Mar 2002

Porter Timothy R, Richards Frances M, Houlston Richard S, Evans D Gareth R, Jankowski Janusz A, Macdonald Fiona, Norbury Gail, Payne Stewart J, Fisher Samantha A, Tomlinson Ian, Maher Eamonn R

Abstract excerpt

The molecular basis for most non-HNPCC familial colorectal cancer cases is unknown, but there is increasing evidence that common genetic variants may play a role. We investigated the contribution of polymorphisms in two genes implicated in the pathogenesis of colorectal cancer, cyclin D1 (CCND1) and E-cadherin (CDH1), to familial and sporadic forms of the disease. The CCND1 870A/G polymorphism is thought to...

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Identifiers

PMID: 11896626
DOI: 10.1038/sj.onc.1205245

Genes

CCND1
CDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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