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Article

The association of cyclin D1 G870A and E-cadherin C-160A polymorphisms with the risk of colorectal cancer in a case control study and meta-analysis.

International journal of cancer - 1 Jun 2008

Tan Xiang-Lin, Nieters Alexandra, Kropp Silke, Hoffmeister Michael, Brenner Hermann, Chang-Claude Jenny

Abstract excerpt

Cyclin D1 (CCND1) and E-cadherin (CDH1) have been shown to be important genes of the beta-catenin/LEF pathway that is involved in colorectal carcinogenesis. However, epidemiological studies on relationship between genetic variants of these two genes and colorectal cancer (CRC) have shown inconsistent results. In a population-based case-control study (498 cases and 600 controls), we assessed the association of...

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Identifiers

PMID: 18196581
DOI: 10.1002/ijc.23363

Genes

CCND1
CDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The association of cyclin D1 G870A and E-cadherin C-160A polymorphisms with the risk of colorectal cancer in a case control study and meta-analysis.PMID 18196581Read ↗

Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) alterations to colorectal cancer susceptibility: a case-control study.Semantic proximity Read ↗

The association between CCND1 G870A polymorphism and colorectal cancer risk: A meta-analysis.Semantic proximity Read ↗

E-cadherin (CDH1) gene promoter polymorphism and the risk of colorectal cancer : a meta-analysis.Semantic proximity Read ↗

E-cadherin (CDH1) gene -160C/A polymorphism and the risk of colorectal cancer: A meta-analysis involving 17,291 subjects.Semantic proximity Read ↗

Association between the Epithelial Cadherin - 160C/A Polymorphism and Colorectal Cancer Risk: Evidence from a Meta-Analysis.Semantic proximity Read ↗

Cyclin D1 G870A polymorphism contributes to colorectal cancer susceptibility: evidence from a systematic review of 22 case-control studies.Semantic proximity Read ↗

Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer.Semantic proximity Read ↗

The CDH1-160C>A polymorphism is a risk factor for colorectal cancer.Semantic proximity Read ↗

Cyclin D1 G870A polymorphism and breast cancer risk: a meta-analysis comprising 9,911 cases and 11,171 controls.Semantic proximity Read ↗

Association between cyclin D1 (CCND1) G870A polymorphism and gastric cancer risk: a meta-analysis.Semantic proximity Read ↗

The cyclin D1 G870A polymorphism and colorectal cancer susceptibility: a meta-analysis of 20 populations.Semantic proximity Read ↗

Lack of Association between the CDH1 -160C>A Polymorphism and Risk of Gastrointestinal Cancer - a Meta-Analysis.Semantic proximity Read ↗

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