Article
Effects of genetic background on prostate and taste bud carcinogenesis due to SV40 T antigen expression under probasin gene promoter control.
Carcinogenesis - 1 Mar 2002
Asamoto Makoto, Hokaiwado Naomi, Cho Young-Man, Shirai Tomoyuki
Abstract excerpt
The incidence of prostate carcinomas in African-American men is greater than in white men, indicating genetic factors are involved in risk of this neoplasia. Recently, we have developed a transgenic rat model of prostate cancer, featuring development of malignancies within 15 weeks of age at very high incidence. Male transgenic rats with a Sprague-Dawley genetic background were mated with wild-type females of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
