Article
Androgen-dependent prostate epithelial cell selection by targeting ARR(2)PBneo to the LPB-Tag model of prostate cancer.
Laboratory investigation; a journal of technical methods and pathology - 1 Oct 2006
Wang Yongqing, Kasper Susan, Yuan Jialing, Jin Ren Jie, Zhang Jianfeng, Ishii Kenichiro, Wills Marcia L, Hayward Simon W, Matusik Robert J
Abstract excerpt
Cell cultures representing different stages of prostatic carcinoma will be a useful tool allowing a more complete understanding of the role of individual genes in tumorigenesis. We used the androgen-regulated probasin promoter linked to the neomycin phosphotransferase (Neo) gene, to generate the ARR(2)PBneo transgenic mouse model. Development was normal and all six ARR(2)PBneo transgenic founder lines expressed...
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