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Article

Genetic alterations in the development of mammary and prostate cancer in the C3(1)/Tag transgenic mouse model.

International journal of oncology - 1 Feb 1998

Yoshidome K, Shibata M A, Maroulakou I G, Liu M L, Jorcyk C L, Gold L G, Welch V N, Green J E

Abstract excerpt

We have generated a transgenic mouse model in which female mice develop ductal mammary adenocarcinomas and male mice develop prostatic adenocarcinomas by using a transgene containing the hormone-responsive rat prostatic steroid binding protein 5' flanking region C3(1) fused to the simian virus 40 (SV40) large T antigen. We have identified some genetic alterations during mammary and prostate tumor progression: (i)...

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PMID: 9458374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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